Diagnóstico Repetido de COVID-19: Influência da Modulação Automática e Capacidade Funcional de Pessoas Idosas

Abstract

Objective: To analyze the influence of the number of times of diagnosis of covid-19 on autonomic modulation and functional capacity in the older people. Materials and methods: This is a quantitative cross-sectional study, which included 38 without covid-19 (Control), 25 who had covid-19 once (C1), and 16 infected with covid-19 two or more times (C2+). Anamnesis, anthropometry, blood pressure collection, 6-minute walk test, Time Up and Go and resting electrocardiogram were performed. Data were analyzed by Kolmogorov-Smirnov, followed by 1-way ANOVA and Tukey-Kramer Multiple Comparisons Test, with significance for p≤0.05. Results: No differences were found between age, Body Mass Index, systolic and diastolic blood pressure. In terms of autonomic variables, there was a reduction in NN intervals (p=0.04) when comparing C1 and C2+, an increase in LF/HF when comparing C2+ to the control group and C1 (p=0.02), a reduction in SD2 (p=0.01) between C1 and C2+ when compared to the control group, and a reduction in Alpha 1 when comparing the control group to the C1 and C2+ groups (p=0.001). Conclusion: It is suggestive that individuals with a higher number of reinfections may be subject to reduced Heart Rate Variability and increased cardiac autonomic dysfunction. We did not observe statistical difference for (6MWT) and (TUG) between the groups.